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研究组长

姓  名: 黄铭坤 研 究 组: 植物功能基因组研究组
职  务: 研究组长 职  称: 副研究员
通讯地址: 江西省南昌市溪霞镇溪霞农业园科研中心
邮政编码: 330114 电子邮箱: huangmk@lsbg.cn
姓  名: 黄铭坤
研 究 组: 植物功能基因组研究组
职  务: 研究组长
职  称: 副研究员
通讯地址: 江西省南昌市溪霞镇溪霞农业园科研中心
邮政编码: 330114
电子邮箱: huangmk@lsbg.cn

学习经历:

2012年9月-2016年1月 中国科学院华南植物园 博士

2009年9月-2012年6月 华南农业大学 硕士

2005年9月-2009年6月 华南农业大学 学士 

 

工作经历:

2022年1月-至今 江西省、中国科学院庐山植物园

2018年3月-2021年12月 香港中文大学

2016年3月-2018年2月 北京中药研究所/北京诺禾致源生物科技公司

  

研究领域:

1. 植物功能基因组学、生物信息学 (Dry lab);

2. 植物分子生物学、植物基因编辑 (Wet lab); 


承担科研项目情况:

1. 国家自然基金地区面上项目,主持

2. 江西省高层次与紧缺型人才计划项目,主持

3. 江西省自然科学基金面上项目,主持

4. 庐山植物园专项基金,主持

5. 香港中文大学优秀博士后基金项目 (Impact Postdoctoral Fellowship Scheme of The Chinese University of Hong Kong) ,主持

6. 香港AoE 项目 (Hong Kong Research Grants Council Area of Excellence Scheme, AoE/M-403/16),参与

7. 香港罗桂祥基金项目 (Lo Kwee-Seong Biomedical Research Fund),参与

8. 中国博士后创新计划 (BX201600155) 基金项目,主持


论文及论著:

--2024--

1. Huang, M.#, Hu, Y., Zhang, L., Yang, H., Feng, C., Jiang, C., Xie, N., Liu, D., Chen, S., Wang, J., et al. (2024). Decoding the chromatin accessibility in Andrographis paniculata genome, a case study of genome-wide investigation of the cis-regulatory elements in medicinal plants. Acta Pharm Sin B 14:4179-4182. 10.1016/j.apsb.2024.06.012.

2. Jia, T., Yang, H., Zhou, D., Zhao, S., Wang, J., Zhang, T., Huang, M., Kong, D., and Liu, Y. (2024). Establishment of a Genetic Transformation and Gene Editing Method by Floral Dipping in Descurainia sophia. Plants (Basel) 1310.3390/plants13202833.

3. Wang, J., Pu, Z., Zhang, W., Qu, M., Gao, L., Pan, W., Sun, Y., Fu, C., Zhang, L., Huang, M.#, Yufang Hu#. (2024). Identification of the New GmJAG1 Transcription Factor Binding Motifs Using DAP-Seq. Plants (Basel) 1310.3390/plants13121708.

4. Yung, W.S., Wang, Q., Chan, L.Y., Wang, Z., Huang, M., Li, M.W., Wong, F.L., and Lam, H.M. (2024). DNA Hypomethylation Is One of the Epigenetic Mechanisms Involved in Salt-Stress Priming in Soybean Seedlings. Plant Cell Environ 10.1111/pce.15297.

专利申请

冯晨、黄铭坤、刘亚芳、张弋、张强,2024,协同抑制乙酰胆碱酯酶的加兰他敏组合物,发明专利,CN116570600B

--2023--

1. Huang, M#., Zhang, L., Yung, W.-S., Hu, Y., Wang, Z., Li, M.-W., and Lam, H.-M. (2023). Molecular evidence for enhancer–promoter interactions in light responses of soybean seedlings. Plant Physiol 10.1093/plphys/kiad487.

2. Su, W., Zhu, C., Fan, Z., Huang, M., Lin, H., Chen, X., Deng, C., Chen, Y., Kou, Y., Tong, Z., et al. (2023). Comprehensive metabolome and transcriptome analyses demonstrate divergent anthocyanin and carotenoid accumulation in fruits of wild and cultivated loquats. Front Plant Sci 14:1285456. 10.3389/fpls.2023.1285456.

3. Zhang, L., Yung, W.-S., Hu, Y., Wang, L., Sun, W., and Huang, M#. (2023). Establishment of a convenient ChIP-seq protocol for identification of the histone modification regions in the medicinal plant Andrographis paniculata. Medicinal Plant Biology 210.48130/MPB-2023-0006.

4. Zhu, W., Huang, J., Huang, M., and Lu, P. (2023). ATAC-Me simultaneously decodes chromatin accessibility and DNA methylation. Trends Plant Sci 28:968-969. 10.1016/j.tplants.2023.05.013.

--2022--

1. Zhang L, Yung WS, Huang M# (2022) STARR-seq for high-throughput identification of plant enhancers. Trends Plant Sci 27(12):1296-1297

2. Zhang L, Yung WS, Sun W, Li MW, Huang M# (2022) Genome-wide characterization of Nuclear Factor Y transcription factors in Fagopyrum tataricum. Physiol Plant: e13668

3. Zhang L, Yung WS, Wang Z, Li MW, Huang M# (2022) Optimization of an Efficient Protoplast Transformation System for Transient Expression Analysis Using Leaves of Torenia fournieri. Plants (Basel) 11(16)

4. Huang M, Zhang L, Zhou L, Yung WS, Wang Z, Xiao Z, Wang Q, Wang X, Li MW, Lam HM# (2022) Identification of the accessible chromatin regions in six tissues in the soybean. Genomics 114(3): 110364

5. Wang G, Li X, Shen W, Li M-W, Huang M, Zhang J, Li H# (2022) The chromatin accessibility landscape of pistils and anthers in rice. Plant Physiol

6. Wang Z, Huang C, Niu Y, Yung W-S, Xiao Z, Wong F-L, Huang M, Wang X, Man C-K, Sze C-C, Liu A, Wang Q, Chen Y, Liu S, Wu C, Liu L, Hou W, Han T, Li M-W, Lam H-M# (2022) QTL analyses of soybean root system architecture revealed genetic relationships with shoot-related traits. Theoretical and Applied Genetics 135(12): 4507-4522

7. Xiao Z, Wang Q, Li M-W, Huang M, Wang Z, Xie M, Varshney RK, Nguyen HT, Chan T-F, Lam H-M# (2022) Wildsoydb DataHub: a platform for accessing soybean multiomic datasets across multiple reference genomes. Plant Physiol

--2021--

1. Huang M, Li MW, Lam HM# (2021) How noncoding open chromatin regions shape soybean domestication. Trends Plant Sci 26(9):876-878.

2. Huang M, Zhang L, Zhou L, Wang M, Yung W-S, Wang Z, Duan S, Xiao Z, Wang Q, Wang X, Li M-W, Lam H-M# (2021) An expedient survey and characterization of the soybean JAGGED 1 (GmJAG1) transcription factor binding preference in the soybean genome by modified ChIPmentation on soybean protoplasts. Genomics 113(1): 344-355

3. Huang M, Zhang L, Zhou LM, Yung WS, Li MW, Lam HM# (2021) Genomic Features of Open Chromatin Regions (OCRs) in Wild Soybean and Their Effects on Gene Expressions. Genes 12(5)

4. Zhang L, Zhou L, Yung WS, Su W, Huang M# (2021) Ectopic expression of Torenia fournieri TCP8 and TCP13 alters the leaf and petal phenotypes in Arabidopsis thaliana. Physiol Plant

5. Yung WS, Wang Q, Huang M, Wong FL, Liu A, Ng MS, Li KP, Sze CC, Li MW, Lam HM# (2021) Priming-induced alterations in histone modifications modulate transcriptional responses in soybean under salt stress. Plant J

6. Wang G, Li X, Ye N, Huang M, Feng L, Li H, Zhang J# (2021) OsTPP1 regulates seed germination through the crosstalk with abscisic acid in rice. New Phytol

--2021以前--

1. Sun W, Leng L, Yin Q, Xu M, Huang M, Xu Z, Zhang Y, Yao H, Wang C, Xiong C, Chen S, Jiang C, Xie N, Zheng X, Wang Y, Song C, Peters RJ, Chen S# (2019) The genome of the medicinal plant Andrographis paniculata provides insight into the biosynthesis of the bioactive diterpenoid neoandrographolide. Plant J 97(5): 841-857

2. Hu Y, Zhou L, Huang M, He X, Yang Y, Liu X, Li Y, Hou X# (2018) Gibberellins play an essential role in late embryogenesis of Arabidopsis. Nature Plants 4(5): 289-298

3. Liu X, Hu P, Huang M, Tang Y, Li Y, Li L, Hou X# (2016) The NF-YC–RGL2 module integrates GA and ABA signalling to regulate seed germination in Arabidopsis. Nature Communications 7(1): 12768

4. Huang M, Hu Y, Liu X, Li Y, Hou X# (2015) Arabidopsis LEAFY COTYLEDON1 controls cell fate determination during post-embryonic development. Front Plant Sci 6: 955

5. Huang M, Hu Y, Liu X, Li Y, Hou X# (2015) Arabidopsis LEAFY COTYLEDON1 Mediates Postembryonic Development via Interacting with PHYTOCHROME-INTERACTING FACTOR4. Plant Cell 27(11): 3099-3111

6. Huang M, Ma C, Yu R, Mu L, Hou J, Yu Y, Fan Y# (2015) Concurrent changes in methyl jasmonate emission and the expression of its biosynthesis-related genes in Cymbidium ensifolium flowers. Physiol Plant 153(4): 503-512

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